Hmm, interesting question. Total silence would be a complete lack of sound vibrations. I imagine it would be like temperature, you can get very close but you can never reach absolute silence because there will always be some vibrations left.
On a more practical note, you will always be able to hear things like the sounds of your own body. Even just your blood pumping. So to have total silence to hear, you’d have to be dead, then you couldn’t hear it.
Even if there were no sound from your environment OR your body (!), the nerves that carry the signals probably have a bit of electrical noise. So if everything was quiet enough you could hear your own nerves.